Two people were injured when their vehicle rolled over Sunday evening on Interstate 99 near mile marker 83 in Centre County.
State police at Rockview said the driver, a man whom they did not identify, was traveling south when he lost control of his vehicle.
The vehicle crossed the median, flipped over and landed in the northbound lanes, police said.
The driver and a passenger received what police called minor to moderate injuries and were taken to Mount Nittany Medical Center.
Additional information was not available late Sunday.