Cher will bring her Dressed to Kill tour to the Bryce Jordan Center in September, the venue announced Wednesday.
The Sept. 24 concert also will feature Pat Benatar and Neil Giraldo.
The pop superstar last performed at Penn State in 2003.
Tickets go on sale at 10 a.m. Monday at Ticketmaster.com, the Bryce Jordan Center box office, Eisenhower Auditorium and Penn State Downtown Theatre, or by phone at 800-745-3000.
Ticket prices are $39.50, $97 and $131.50.