The right-hand lanes of Interstate 80 near Bellefonte will close starting Monday as guide rail and shoulder work progresses.
The lanes will be closed for two to three weeks, according to the state Department of Transportation. Traffic will be directed to the left lanes.
The work zone will be between mile markers 170 and 164 in both directions. The speed limit will be reduced to 45 miles per hour.
PennDOT expects the work to finish by mid-October.