Carlisle outscored State College by 10 in the third quarter en route to a 57-47 victory on Friday night.
The Little Lions (9-9) trailed by two at halftime before the Thundering Herd (14-6) broke it open with an 18-8 run in the third quarter.
Alex McCann scored 13 points to lead State College.
Deshawn Millington paced Carlisle with 20 points, and Jordan Purcell added 17.
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