Penn State was in good shape leading by one goal heading into the final period on Saturday.
However, Syracuse came alive for a four-goal third period to top the Nittany Lions 4-1.
Abby Welch scored the lone Penn State goal with 9:30 left in the second period. Daniela Paniccia had 30 saves for the Nittany Lions.
Allie Munroe (2), Laurence Porlier and Brooke Avery tallied the Orange’s goals.